HPE ProLiant DL385 Gen11 Rack Server – Dual AMD EPYC, 6 TB DDR5, PCIe Gen5


Accelerator-optimized 2U server featuring dual AMD EPYC CPUs (up to 320 cores total), up to 6 TB DDR5 memory, PCIe Gen5 & EDSFF support, up to 8 GPUs, and robust silicon-root security—all managed via HPE iLO 6.

  • ProLiant DL385 Gen11
  • Form Factor: 2U Rack Mount
  • Supported Processor: 4th Gen AMD EPYC
  • Total Memory Slots: 24 DIMMs
  • PCI slots: 8 PCIe Gen5 slots
  • Max Memory: 6.0 TB with 256 GB DDR5
  • Max Cores: 192 Cores
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  • Next-Level CPU Performance
    Supports 4th & 5th Gen AMD EPYC™ processors, delivering up to 160 cores and 1152 MB L3 cache per socket for extreme parallel processing.

  • Large-Scale DDR5 Memory
    Equipped with 24 DIMM slots per processor, it supports up to 6 TB of DDR5 memory at speeds up to 6400 MT/s.

  • PCIe Gen5 & EDSFF Storage Ready
    Offers two PCIe Gen5 x16 slots, two OCP slots, and supports latest EDSFF (E3.S) NVMe drives for ultra-fast data access.

  • GPU Acceleration
    Supports up to 8 single-width or 4 double-width GPUs, ideal for AI, ML, and HPC acceleration.

  • Hardware-Rooted Security
    Features HPE’s silicon root of trust and AMD Secure Processor, enabling secure boot, runtime integrity validation, and firmware auto-recovery.

  • Remote Management with iLO 6
    Integrated HPE iLO 6 offers remote console access, firmware automation, and health monitoring via RESTful API.

  • Flexible Cooling & Power
    Includes standard or performance fan kits, optional liquid cooling, and up to 2200 W hot-plug power supplies for reliability under heavy loads.

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Technical Specifications

Feature Specification
Model HPE ProLiant DL385 Gen11
Form Factor 2U, dual-socket rack server
CPUs 2× AMD EPYC 9004/9005 Series (up to 160 cores/socket, 320 cores total)
Memory Up to 6 TB DDR5 across 24 DIMMs/socket (48 total)
PCIe Slots Up to 8× PCIe Gen5 + 2× OCP slots
GPU Support Up to 8× single or 4× double-width GPUs
Storage Bays Up to 24× SFF / 12× LFF / 36× E3.S EDSFF, with mid/rear bay options
iLO Version HPE iLO 6
Security Silicon root of trust, secure firmware, AMD Secure Processor
Power Supply Up to 2× 2200 W hot-plug; liquid-cooling optional

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